Organized in 1974, Jackson County EMS originated staffing two ambulances with 12 employees; one in Jefferson and one in Commerce. EMS crews received calls for assistance from the public on a telephone that was answered by the crews themselves. In the event that both ambulances were out, the phone rang to BJC hospital and they contacted the ambulances by radio. Over the years, Jackson County increased its number of ambulances and personnel to respond to the needs of Jackson County.

Today, Jackson County EMS staffs seven advanced life support ambulances with 40 full-time employees and more than 50 part-time employees. Ambulances are located throughout the county and equipped to handle any medical, cardiac or trauma related emergency.